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. 1996 Nov;70(11):8160-4.
doi: 10.1128/JVI.70.11.8160-8164.1996.

The reovirus nonstructural protein sigma1NS is recognized by murine cytotoxic T lymphocytes

L M Hoffman  1 , K T Hogan, L W Cashdollar
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The reovirus nonstructural protein sigma1NS is recognized by murine cytotoxic T lymphocytes

L M Hoffman et al. J Virol. 1996 Nov.

Abstract

The cytotoxic T-lymphocyte (CTL) response in reovirus-infected C3H mice was investigated by using reovirus-vaccinia virus recombinants. Results of cytotoxicity assays indicated that the nonstructural protein sigma1NS elicited a significant CTL response. Experiments with sigma1NS-specific CTL lines showed that both strain-specific and cross-reactive epitopes exist in the sigma1NS protein.

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