Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Nov;70(11):8195-8.
doi: 10.1128/JVI.70.11.8195-8198.1996.

The highly O-glycosylated glycoprotein gp2 of equine herpesvirus 1 is encoded by gene 71

J E Wellington  1 , G P Allen, A A Gooley, D N Love, N H Packer, J X Yan, J M Whalley
Affiliations

The highly O-glycosylated glycoprotein gp2 of equine herpesvirus 1 is encoded by gene 71

J E Wellington et al. J Virol. 1996 Nov.

Abstract

There have been conflicting reports regarding the gene assignment of the high-molecular-mass envelope glycoprotein gp2 (gp300) of equine herpesvirus 1. Here, we provide an unequivocal demonstration that gp2 is encoded by gene 71. gp2 that was purified with a defining monoclonal antibody was cleaved internally to yield a 42-kDa protein encoded by gene 71. Amino acid composition data and N-terminal sequence analysis of a tryptic peptide identified gp2 as the product of equine herpesvirus 1 gene 71 with the SWISS-PROT database. Analysis of gp2's monosaccharide composition and the 42-kDa subunit showed that the high level of O glycosylation occurs on the serine/threonine-rich region upstream of the cleavage site.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Virology. 1992 Jun;188(2):545-57 - PubMed
    1. Virology. 1992 Jul;189(1):304-16 - PubMed
    1. Glycobiology. 1991 Mar;1(2):131-8 - PubMed
    1. J Gen Virol. 1992 Nov;73 ( Pt 11):2933-40 - PubMed
    1. Arch Virol. 1993;128(1-2):143-54 - PubMed

Publication types

Substances

LinkOut - more resources