The interaction of short-chain aralkyl alcohols and amines with the erythrocyte membrane
- PMID: 88950
The interaction of short-chain aralkyl alcohols and amines with the erythrocyte membrane
Abstract
Erythrocytes in isotonic saline are hemolyzed by benzyl alcohol and by 2-phenylethanol, but not by the corresponding amines nor by the ring-or side-chain-hydroxylated analogs. All these compounds could however interact with the erythrocyte membrane since: a) they facilitated the hemolytic effect of benzyl alcohol and/or of phenylelytic effect of benzyl alcohol and/or of phenylethanol; b) they exerted a protective effect against controlled hypotonic hemolysis.
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