Clinical Trial
doi: 10.1016/0006-3223(95)00494-7.
Alprazolam premedication and 35% carbon dioxide vulnerability in panic patients
Affiliations
- PMID: 8896779
- DOI: 10.1016/0006-3223(95)00494-7
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Clinical Trial
Alprazolam premedication and 35% carbon dioxide vulnerability in panic patients
Biol Psychiatry.
.
Abstract
A group of 20 patients who met the DSM-III-R criteria for panic disorder with or without agoraphobia underwent a 35% carbon dioxide (CO2) challenge after either 1 mg alprazolam or placebo in a double-blind, randomized, cross-over design. Despite the anxiolytic potential of alprazolam, it produced no significant effects on CO2-induced anxiety and panic symptomatology when compared to placebo.
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