Determination by photon correlation spectroscopy of particle size distributions in lipid vesicle suspensions
- PMID: 890039
- PMCID: PMC1473325
- DOI: 10.1016/S0006-3495(77)85586-0
Determination by photon correlation spectroscopy of particle size distributions in lipid vesicle suspensions
Abstract
A method of determining particle size distributions in lipid vesicle preparations is outlined. A vesicle suspension is modeled as a polydisperse mixture of spherical shells. The distribution of particle sizes in this mixture is approximated by a continuous, piecewise linear function called a first-order spline. Excellent simultaneous fits to photon correlation spectroscopy data gathered at several different angles are presented. An error analysis is included to indicate the resolution of the method.
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