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Review
. 1996 Oct;8(5):637-42.
doi: 10.1016/s0952-7915(96)80079-3.

Oncogenic proteins as tumor antigens

M L Disis  1 , M A Cheever
Affiliations
Review

Oncogenic proteins as tumor antigens

M L Disis et al. Curr Opin Immunol. 1996 Oct.

Abstract

Human immune responses to oncogenic proteins have been reported and are continuing to be defined. Immunity to nonmutated overexpressed oncoproteins as well as to mutated or unique cancer-specific oncoproteins has been identified. Immune system based treatments targeting oncogenic proteins have shown therapeutic efficacy in animals models and are currently being translated into human clinical trials.

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