Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Aug 13;2(6084):434-5.
doi: 10.1136/bmj.2.6084.434.

Treatment of liposclerosis of the leg by fibrinolytic enhancement: a preliminary report

N L Browse, P E Jarrett, M Morland, K Burnand

Treatment of liposclerosis of the leg by fibrinolytic enhancement: a preliminary report

N L Browse et al. Br Med J. .

Abstract

Fourteen patients with longstanding lipodermatosclerosis of their lower legs, secondary to venous disease in 11, were treated for three months with stanozolol, a drug that enhances fibrinolytic activity. No other treatment was given and no change made in existing treatment. All the patients improved. Two were cured in three months, three were able to stop treatment in the next three to 11 months, and the other nine continued to improve. Fibrinolytic enhancement, with stanozolol, seems to be a worthwhile addition to the treatment of venous liposclerosis and deserves further study.

PubMed Disclaimer

References

    1. Clin Sci (Lond). 1957 Nov;16(4):645-50 - PubMed
    1. Arch Biochem Biophys. 1952 Oct;40(2):346-51 - PubMed
    1. Br J Surg. 1976 Aug;63(8):660-1 - PubMed
    1. Br Med J. 1977 Feb 19;1(6059):478-81 - PubMed
    1. Br J Haematol. 1972 May;22(5):543-59 - PubMed

LinkOut - more resources