Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Jan;7(1):13-5.
doi: 10.1007/s003359900004.

Cardiac and skeletal muscle troponin I isoforms are encoded by a dispersed gene family on mouse chromosomes 1 and 7

J L Guenet  1 , D Simon-Chazottes, M Gravel, K E Hastings, S Schiaffino
Affiliations

Cardiac and skeletal muscle troponin I isoforms are encoded by a dispersed gene family on mouse chromosomes 1 and 7

J L Guenet et al. Mamm Genome. 1996 Jan.

Abstract

We mapped the locations of the genes encoding the slow skeletal muscle, fast skeletal muscle, and cardiac isoforms of troponin I (Tnni) in the mouse genome by interspecific hybrid backcross analysis of species-specific (C57BL/6 vs Mus spretus) restriction fragment length polymorphisms (RFLPs). The slow skeletal muscle troponin I locus (Tnni1) mapped to Chromosome (Chr) 1. The fast skeletal muscle troponin I locus (Tnni2), mapped to Chr 7, approximately 70 cM from the centromere. The cardiac troponin I locus (Tnni3) also mapped to Chr 7, approximately 5-10 cM from the centromere and unlinked to the fast skeletal muscle troponin I locus. Thus, the troponin I gene family is dispersed in the mouse genome.

PubMed Disclaimer

References

    1. Hum Genet. 1991 Nov;88(1):101-4 - PubMed
    1. Curr Top Microbiol Immunol. 1986;127:109-13 - PubMed
    1. Nature. 1978 Jan 5;271(5640):31-5 - PubMed
    1. Adv Protein Chem. 1986;38:1-67 - PubMed
    1. Rev Physiol Biochem Pharmacol. 1990;116:1-76 - PubMed

Publication types

Grants and funding

LinkOut - more resources