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. 1996 Mar;34(3):717-9.
doi: 10.1128/jcm.34.3.717-719.1996.

Controlled study of cytolethal distending toxin-producing Escherichia coli infections in Bangladeshi children

M J Albert  1 , S M Faruque, A S Faruque, K A Bettelheim, P K Neogi, N A Bhuiyan, J B Kaper
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Controlled study of cytolethal distending toxin-producing Escherichia coli infections in Bangladeshi children

M J Albert et al. J Clin Microbiol. 1996 Mar.

Abstract

The role of cytolethal distending toxin (CDT)-producing Escherichia coli, a newly described category of E. coli, in the causation of diarrhea was studied by screening E. coli isolates from 546 children < 5 years of age with diarrhea and 215 matched controls without diarrhea by using a specific DNA probe. Although CDT-positive E. coli strains were isolated from more children with diarrhea than from healthy controls (3.1 versus 0.93%), this difference did not reach statistical significance (P = 0.082). All CDT-positive strains also possessed the virulence factors of enteropathogenic E. coli or enteroaggregative E. coli isolates.

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