Eosinophils negatively regulate eosinophilopoiesis by decreasing IL-5 levels
- PMID: 8906102
- DOI: 10.1159/000237403
Eosinophils negatively regulate eosinophilopoiesis by decreasing IL-5 levels
Abstract
The effect of mature eosinophils on eosinophilopoiesis was studied. Mature eosinophils decreased the interleukin-5 (IL-5) level after incubation with IL-5 and suppressed IL-5 release from non-adherent mononuclear cells. These findings suggest that eosinophils negatively regulate eosinophilopoiesis by decreasing the IL-5 level.
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