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. 1996:111 Suppl 1:2-4.
doi: 10.1159/000237403.

Eosinophils negatively regulate eosinophilopoiesis by decreasing IL-5 levels

H Enokihara  1 , T Koike, Y Nakamura, K Yamashiro, N Tsuruoka, K Saito, S Furusawa
Affiliations

Eosinophils negatively regulate eosinophilopoiesis by decreasing IL-5 levels

H Enokihara et al. Int Arch Allergy Immunol. 1996.

Abstract

The effect of mature eosinophils on eosinophilopoiesis was studied. Mature eosinophils decreased the interleukin-5 (IL-5) level after incubation with IL-5 and suppressed IL-5 release from non-adherent mononuclear cells. These findings suggest that eosinophils negatively regulate eosinophilopoiesis by decreasing the IL-5 level.

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