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Comparative Study
. 1996 Nov;40(11):2669-70.
doi: 10.1128/AAC.40.11.2669.

In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae

C C Kuo  1 , L A Jackson, A Lee, J T Grayston
Affiliations
Comparative Study

In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae

C C Kuo et al. Antimicrob Agents Chemother. 1996 Nov.

Abstract

The in vitro susceptibilities of Chlamydia pneumoniae isolates to macrolide, tetracycline, and quinolone antibiotics were determined. Tetracycline, clarithromycin, and erythromycin had the lowest MICs in the first cell culture passage. Azithromycin required the lowest concentration for complete inhibition of inclusion formation on the second pass into antibiotic-free medium, likely reflecting its high intracellular concentrations.

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