Zinc, cadmium, and mercury complexes of 5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine (dmtp). Preparation, spectroscopic characterization, and biological activity. X-ray crystal structures of [Zn(dmtp)2Br2], [Hg(dmtp)2Cl2], and [Hdmtp]2[CdBr4]. 2H2O

Abstract

The preparation and spectroscopic characterization of a series of dmtp complexes of Zn, Cd, and Hg, where dmtp is 5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidine, is reported. Crystal structure analyses of [Zn(dmtp)2Br2] and [Hg(dmtp)2Cl2] reveal distorted tetrahedral geometries about the central atoms and the dmtp ligands to coordinate via the N(3) atom exclusively. In the X-ray structure of [Hdmtp]2[CdBr4].2H2O, the [Hdmtp]+ cation is protonated at the N(3) atom, there being no significant interaction between Hdmtp and cadmium. A study of the antimicrobial activity of the complexes shows that the [Cd(dmtp)X2(OH2)] (X = Cl, Br) compounds display activity against two strains.