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. 1977 Sep 15;33(9):1198-200.
doi: 10.1007/BF01922326.

Methiothepin and a 5-HT pathway to rat substantia nigra

A Dray, N R Oakley

Methiothepin and a 5-HT pathway to rat substantia nigra

A Dray et al. Experientia. .

Abstract

Methiothepin reduced both median-raphe evoked and exogenous 5-HT depression of single substantia nigra neurones. While this is compatible with a serotonin releasing pathway, additional interactions of methiothepin with exogenous dopamine suggest the need for further pharmacological confirmation.

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