Pharmacology of the neurotransmitter release enhancer linopirdine (DuP 996), and insights into its mechanism of action
- PMID: 8920211
- DOI: 10.1016/s1054-3589(08)60281-1
Pharmacology of the neurotransmitter release enhancer linopirdine (DuP 996), and insights into its mechanism of action
Similar articles
-
Selectivity of linopirdine (DuP 996), a neurotransmitter release enhancer, in blocking voltage-dependent and calcium-activated potassium currents in hippocampal neurons.J Pharmacol Exp Ther. 1998 Aug;286(2):709-17. J Pharmacol Exp Ther. 1998. PMID: 9694925
-
2-Fluoro-4-pyridinylmethyl analogues of linopirdine as orally active acetylcholine release-enhancing agents with good efficacy and duration of action.J Med Chem. 1998 Nov 5;41(23):4615-22. doi: 10.1021/jm9803424. J Med Chem. 1998. PMID: 9804701
-
Effect of the putative cognitive enhancer, linopirdine (DuP 996), on quantal parameters of acetylcholine release at the frog neuromuscular junction.Br J Pharmacol. 1994 Apr;111(4):1103-10. doi: 10.1111/j.1476-5381.1994.tb14858.x. Br J Pharmacol. 1994. PMID: 8032596 Free PMC article.
-
Reduction of spike frequency adaptation and blockade of M-current in rat CA1 pyramidal neurones by linopirdine (DuP 996), a neurotransmitter release enhancer.Br J Pharmacol. 1995 Aug;115(7):1163-8. doi: 10.1111/j.1476-5381.1995.tb15019.x. Br J Pharmacol. 1995. PMID: 7582539 Free PMC article.
-
Pharmacological Targeting of Neuronal Kv7.2/3 Channels: A Focus on Chemotypes and Receptor Sites.Curr Med Chem. 2018;25(23):2637-2660. doi: 10.2174/0929867324666171012122852. Curr Med Chem. 2018. PMID: 29022505 Review.
Cited by
-
Mouse models of Kcnq2 dysfunction.Epilepsia. 2022 Nov;63(11):2813-2826. doi: 10.1111/epi.17405. Epub 2022 Sep 27. Epilepsia. 2022. PMID: 36047730 Free PMC article. Review.
-
Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains.Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8870-5. doi: 10.1073/pnas.0603376103. Epub 2006 May 30. Proc Natl Acad Sci U S A. 2006. PMID: 16735477 Free PMC article.
-
Roles of specific Kv channel types in repolarization of the action potential in genetically identified subclasses of pyramidal neurons in mouse neocortex.J Neurophysiol. 2016 May 1;115(5):2317-29. doi: 10.1152/jn.01028.2015. Epub 2016 Feb 10. J Neurophysiol. 2016. PMID: 26864770 Free PMC article.
-
Kv7/KCNQ/M and HCN/h, but not KCa2/SK channels, contribute to the somatic medium after-hyperpolarization and excitability control in CA1 hippocampal pyramidal cells.J Physiol. 2005 Aug 1;566(Pt 3):689-715. doi: 10.1113/jphysiol.2005.086835. Epub 2005 May 12. J Physiol. 2005. PMID: 15890705 Free PMC article.
-
Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.Compr Physiol. 2017 Mar 16;7(2):485-581. doi: 10.1002/cphy.c160011. Compr Physiol. 2017. PMID: 28333380 Free PMC article. Review.