[Hemodynamics during combined nociceptive stimulation and stimulation of the amygdaloid complex following treatment of the sensomotor cortex]

Abstract

In acute experiments on cats, changes of the arterial pressue (AP), intracardiac pressure (ICP), and of the blood flow rate following a nociceptive stimulus (NS), electrical stimulation of the lateral nucleus of amygdala (AL), and the combination of these stimuli before and after application of strychnine and potassium chloride on sensorimotor cortical area, were studied. After the application of strychnine and potassium chloride, the stimulation of AL produced weaker pressor reaction; while a nociceptive stimulus was followed by the same changes as in the intact cats. After the application of strychnine, combination of the AL stimulation and NS produced the increase of pressor reaction; while after the application of potassium chloride, the pressor reaction did not change at all or became weaker. After the application of strychnine, the blood flow rate response to the stimuli was similar to the control experiments; after the application of potassium chloride the blood flow rate decreased.