Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1996 Nov;9(5):307-10.
doi: 10.2165/00002512-199609050-00001.

Clinical trials in the elderly. Should we do more?

H J Cameron  1 , B O Williams
Affiliations
Review

Clinical trials in the elderly. Should we do more?

H J Cameron et al. Drugs Aging. 1996 Nov.

Abstract

Much of the information on which treatment decisions are based in elderly patients is derived from studies involving younger adults. The benefit to risk ratio of any given intervention may be quite different in frail older patients with significant comorbidities, and the applicability of such study findings to routine geriatric medical practice is therefore limited. The recruitment of significant numbers of elderly patients into trials is necessary to enable clinicians to make informed and rational therapeutic decisions in this expanding population.

PubMed Disclaimer

References

    1. Age Ageing. 1992 Mar;21(2):95-8 - PubMed
    1. J Gerontol. 1992 Sep;47(5):M137-44 - PubMed
    1. JAMA. 1991 Jun 26;265(24):3255-64 - PubMed
    1. Cancer. 1994 Oct 1;74(7 Suppl):2208-14 - PubMed
    1. Br Med J. 1969 Mar 1;1(5643):536-9 - PubMed

LinkOut - more resources