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. 1996 Oct;12(13):1297-300.
doi: 10.1002/(SICI)1097-0061(199610)12:13%3C1297::AID-YEA13%3E3.0.CO;2-U.

Genetic aspects of carbon catabolite repression of the STA2 glucoamylase gene in Saccharomyces cerevisiae

N N Kartasheva  1 , S V Kuchin, S V Benevolensky
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Genetic aspects of carbon catabolite repression of the STA2 glucoamylase gene in Saccharomyces cerevisiae

N N Kartasheva et al. Yeast. 1996 Oct.

Abstract

Three regulatory genes, known to be required for glucose repression/derepression of some genes in Saccharomyces cerevisiae, were disrupted to study their effects on the carbon-source regulation of the STA2 glucoamylase gene expression. Using a STA2-lacZ fusion it was found that: (1) the MIG1 gene is dispensable for the repression of the STA2 gene; (2) there are two components in the carbon-source repression of STA2: HXK2-dependent and HXK2-independent; and (3) the HAP2 gene seems to be involved in repression rather than activation of the STA2 expression.

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