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. 1977 Jul;30(7):533-40.
doi: 10.7164/antibiotics.30.533.

Fortimicins A and B, new aminoglycoside antibiotics. I. Producing organism, fermentation and biological properties of fortimicins

T Nara, M Yamamoto, I Kawamoto, K Takayama, R Okachi, S Takasawa, T Sato, S Sato
Free article

Fortimicins A and B, new aminoglycoside antibiotics. I. Producing organism, fermentation and biological properties of fortimicins

T Nara et al. J Antibiot (Tokyo). 1977 Jul.
Free article

Abstract

A culture of Micromonospora species MK-70 was found to produce two new antibiotics, fortimicins A and B. Antibacterial and paper chromatographic data on an eluate from IRC-50 treatment of fermentation beers indicated that fortimicins A and B are new antibiotics with broad-spectrum, basic and water-soluble properties. Fortimicin A exhibited potent, unique, broad-spectrum antibacterial activity against Gram-positive and negative bacteria both in vitro and in vivo, while fortimicin B was only weakly active.

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