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. 1996 Apr;46(2):611-4.
doi: 10.1099/00207713-46-2-611.

Rickettsia africae sp. nov., the etiological agent of African tick bite fever

P J Kelly  1 , L Beati, P R Mason, L A Matthewman, V Roux, D Raoult
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Rickettsia africae sp. nov., the etiological agent of African tick bite fever

P J Kelly et al. Int J Syst Bacteriol. 1996 Apr.

Abstract

We propose the name Rickettsia africae sp. nov. (with type strain Z9-Hu) for a distinct species of spotted fever group (SFG) rickettsiae that is the etiological agent of African tick bite fever in humans. This rickettsia has a distinct natural cycle and can be phenotypically distinguished from the other SFG rickettsiae by microimmunofluorescence serotyping, by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and by Western blotting (immunoblotting). Genotypic differences between R. africae and the other SFG rickettsiae can be demonstrated by PCR restriction fragment length polymorphism analysis, pulsed-field gel electrophoresis, and sequencing of the 16S rRNA gene.

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