doi: 10.1111/j.2042-7158.1996.tb07113.x.
Magnetizable solid-phase supports for purification of nucleic acids
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- PMID: 8935162
- DOI: 10.1111/j.2042-7158.1996.tb07113.x
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Magnetizable solid-phase supports for purification of nucleic acids
J Pharm Pharmacol.
1996 Feb.
Abstract
A simple, small scale non-hazardous procedure for the production of magnetizable solid-phase support (MSPS) beads has been developed based on the extrusion of agarose/iron oxide mixtures. The MSPS beads were derivatized using various amine ligands. Derivatized MSPS beads were used to adsorb nucleic acids from aqueous solution and to separate RNA/DNA mixtures.
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