Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1996 Dec;8(6):773-80.
doi: 10.1016/s0955-0674(96)80077-9.

The spindle assembly checkpoint

A D Rudner  1 , A W Murray
Affiliations
Review

The spindle assembly checkpoint

A D Rudner et al. Curr Opin Cell Biol. 1996 Dec.

Abstract

The spindle assembly checkpoint monitors proper chromosome attachment to spindle microtubules and is conserved from yeast to humans. Checkpoint components reside on kinetochores of chromosomes and show changes in phosphorylation and localization as cells proceed through mitosis. Adaptation to prolonged checkpoint arrest can occur by inhibitory phosphorylation of Cdc2.

PubMed Disclaimer

Publication types

LinkOut - more resources