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Review
. 1996 Nov;3(11):895-904.
doi: 10.1016/s1074-5521(96)90178-7.

Matrix metalloproteinases and the development of cancer

L M Coussens  1 , Z Werb
Affiliations
Review

Matrix metalloproteinases and the development of cancer

L M Coussens et al. Chem Biol. 1996 Nov.

Abstract

Proteolytic remodeling of the extracellular matrix is an important aspect of the creation and progression of cancer. Matrix metalloproteinases are important at several points during multi-stage neoplastic progression in tumor cells and responding blood vessels, inflammatory cells and stroma.

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