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Review
. 1996 Oct;6(5):597-602.
doi: 10.1016/s0959-437x(96)80089-x.

Development of the hematopoietic system

S H Orkin  1
Affiliations
Review

Development of the hematopoietic system

S H Orkin. Curr Opin Genet Dev. 1996 Oct.

Abstract

Significant advances have been made in the past year in understanding hematopoietic development. Recent studies have clarified the origin and migration of stem cells in early embryos, established potential roles for homeodomain proteins in controlling the proliferation of progenitor cells and in patterning ventral mesoderm, and demonstrated the effects of nuclear proteins on lineage programming and apoptosis.

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