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. 1996 Nov 20;12(17):1655-7.
doi: 10.1089/aid.1996.12.1655.

HIV type 1 subtypes in Malaysia include B, C, and E

T M Brown  1 , K E Robbins, M Sinniah, T S Saraswathy, V Lee, L S Hooi, B Vijayamalar, C C Luo, C Y Ou, J Rapier, G Schochetman, M L Kalish
Affiliations

HIV type 1 subtypes in Malaysia include B, C, and E

T M Brown et al. AIDS Res Hum Retroviruses. .

Abstract

PIP: Peripheral blood mononuclear cell specimens were collected from 13 HIV-1-infected IV drug users in Kuala Lumpur, Malaysia, as well as one HIV-infected baby, between 1992 and 1993. DNA was then amplified by nested polymerase chain reaction and a 345-bp fragment of the C2V3 region of the env gene was sequenced. 11 of the 14 Malaysian sequences clustered with the B' subtype, one different from the typical subtype B US strains HIVMN and HIVSF2. Two sequences grouped in the C subtype and had sister taxa closer to the Indian C subtype sequences than those from Zambia. The sequence from the infant was identified as a subtype E virus, grouped more closely with subtype E strains from Thailand than subtype E viruses from the Central African Republic.

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