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Review
. 1996 Dec 12;384(6609):529-34.
doi: 10.1038/384529a0.

Host factors and the pathogenesis of HIV-induced disease

A S Fauci  1
Affiliations
Review

Host factors and the pathogenesis of HIV-induced disease

A S Fauci. Nature. .

Abstract

The level of human immunodeficiency virus (HIV) replication in patients reflects a balance between stimulatory and inhibitory host factors (particularly endogenous cytokines). New information concerning the cellular co-receptors for HIV and the cellular tropism of different strains of virus will advance our understanding of HIV-induced pathogenesis and suggests new therapeutic and preventive strategies.

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