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. 1996 Dec;178(23):7010-3.
doi: 10.1128/jb.178.23.7010-7013.1996.

FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant

K Fredrick  1 , J D Helmann
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FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant

K Fredrick et al. J Bacteriol. 1996 Dec.

Abstract

We have used mini-Tn1O mutagenesis to identify negative regulators of sigmaD activity. Nine independent insertions were mapped to five genes: flgM, flgK, fliD, fliS, and fliT, suggesting that FlgM export is regulated similarly in Bacillus subtilis and Salmonella typhimurium. We show that a deletion of flgM can restore sigmaD activity to a sinR null mutant of B. subtilis, although fla/che operon expression is affected by neither SinR nor FlgM.

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