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. 1996 Dec;178(24):7167-72.
doi: 10.1128/jb.178.24.7167-7172.1996.

FtsA is localized to the septum in an FtsZ-dependent manner

S G Addinall  1 , J Lutkenhaus
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FtsA is localized to the septum in an FtsZ-dependent manner

S G Addinall et al. J Bacteriol. 1996 Dec.

Abstract

The localization of the cell division protein FtsA in E. coli was examined. FtsA was found to localize to the septum in a ring pattern as previously shown for FtsZ. The localization of FtsA was completely dependent on the localization of FtsZ. Under a variety of conditions that prevented formation of the Z ring, FtsA was unable to localize. In mutants where FtsZ forms structures in addition to Z rings, the pattern of FtsA duplicated these structures. These results suggest that the Z ring recruits FtsA to the septum.

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