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. 1996 Nov;75(5):453-4.
doi: 10.1136/adc.75.5.453.

Proinflammatory and anti-inflammatory cytokines in meningococcal disease

F A Riordan  1 , O Marzouk, A P Thomson, J A Sills, C A Hart
Affiliations

Proinflammatory and anti-inflammatory cytokines in meningococcal disease

F A Riordan et al. Arch Dis Child. 1996 Nov.

Abstract

Interleukin-10 (IL-10), an anti-inflammatory cytokine, was measured in 131 children with meningococcal disease. IL-10 concentrations were significantly higher in children who died and correlated positively with proinflammatory cytokines. Children who die from meningococcal disease have high IL-10 concentrations, which do not suppress proinflammatory cytokines.

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References

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