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Review
. 1996 May;180(5):1007-12; discussion 1012-5.

[Bovine spongiform encephalopathy. Review of data collected since the statement of February 6, 1996]

[Article in French]
Affiliations
  • PMID: 8963704
Review

[Bovine spongiform encephalopathy. Review of data collected since the statement of February 6, 1996]

[Article in French]
J Brugère-Picoux et al. Bull Acad Natl Med. 1996 May.

Abstract

The observation in 1995 and 1996 of 10 cases of a new variant of Creutzfeldt-Jakob disease (V-CJD) in U.K. suggested a possible relation between this human cases and bovine spongiform encephalopathy (BSE). Recent papers about this topic are reviewed : hypothesis of a possible genetic link between man and cattle, hypothesis of a acquired resistance against the agent of BSE after a previous infection by a less virulent agent of ovine origin, importance of polymorphism at codon 129 according to the hypothesis of a virus-induced amyloidosis, diagnostic test with cerebrospinal fluid, epidemiology of BSE and prediction of future BSE spread.

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