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Review
. 1996 Nov;24(4):994-1000.
doi: 10.1042/bst0240994.

Regulation of second messengers by the inositol polyphosphate 5-phosphatases

C A Mitchell  1 , S Brown, J K Campbell, A D Munday, C J Speed
Affiliations
Review

Regulation of second messengers by the inositol polyphosphate 5-phosphatases

C A Mitchell et al. Biochem Soc Trans. 1996 Nov.

Abstract

The inositol polyphosphate 5-phosphatases are an enlarging family of enzymes that terminate the signals generated by the phosphoinositide kinases and phospholipase C. Given the diverse signalling functions of both the polyphosphoinositides and Ins(1,4,5)P3, it is predicted that the 5-phosphatases will play a critical role in regulating many cellular events, in particular membrane trafficking and cell growth.

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