Subacute sclerosing panencephalitis
- PMID: 8969008
- DOI: 10.1016/s1071-9091(96)80030-1
Subacute sclerosing panencephalitis
Abstract
Subacute sclerosing panencephalitis (SSPE), a neurodegenerative disease caused by a persistent "slow virus infection" with a mutated measles virus, is endemic in much of the developing world. Its incidence will increase in the USA, not only in immigrants, but also because of the 1988-1990 measles epidemic. This report reviews the pathogenesis, clinical and laboratory diagnosis, and future perspectives in treatment and prevention.
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