Case Reports
doi: 10.1111/j.1346-8138.1996.tb02678.x.
Detection of autoantibody against 97-kD antigen by immunoblot, but not by indirect immunofluorescence, in a patient with linear IgA bullous dermatosis
Affiliations
- PMID: 8973030
- DOI: 10.1111/j.1346-8138.1996.tb02678.x
Item in Clipboard
Case Reports
Detection of autoantibody against 97-kD antigen by immunoblot, but not by indirect immunofluorescence, in a patient with linear IgA bullous dermatosis
J Dermatol.
1996 Oct.
Abstract
A case of linear IgA bullous dermatosis in an 85-year-old man is reported. Direct immunofluorescence (IF) of the lesional skin showed linear deposition of IgA and weak deposition of IgG at the basement membrane zone. Although no circulating autoantibody was detected by indirect IF, immunoblotting analysis using NaCl-separated normal human epidermal extracts revealed a circulating IgA antibody which bound to the 97-kD antigen.
Similar articles
-
Linear IgA bullous dermatosis. Characterization of a subset of patients with concurrent IgA and IgG anti-basement membrane autoantibodies.Arch Dermatol. 1995 Dec;131(12):1432-7. doi: 10.1001/archderm.131.12.1432. Arch Dermatol. 1995. PMID: 7492134
-
Linear IgA bullous dermatosis with circulating IgG autoantibodies to the 230 kD epidermal antigen.J Dermatol. 1998 Aug;25(8):503-9. doi: 10.1111/j.1346-8138.1998.tb02444.x. J Dermatol. 1998. PMID: 9769594
-
A child with antibodies targeting both linear IgA bullous dermatosis and bullous pemphigoid antigens.Arch Dermatol. 1995 Dec;131(12):1438-42. Arch Dermatol. 1995. PMID: 7492135
-
A subepidermal blistering dermatosis associated with coexistent IgG and IgA anti-dermal basement membrane zone antibodies; demonstration of IgG antibodies reactive against a 200-kDa dermal antigen.Eur J Dermatol. 2002 Nov-Dec;12(6):603-6. Eur J Dermatol. 2002. PMID: 12459541 Review.
-
Clinical correlations of linear IgA deposition at the cutaneous basement membrane zone.J Am Acad Dermatol. 1989 May;20(5 Pt 1):761-70. doi: 10.1016/s0190-9622(89)70087-6. J Am Acad Dermatol. 1989. PMID: 2654216 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous
