Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Sep;75(3):242-4.
doi: 10.1136/adc.75.3.242.

Defective growth hormone secretion in children with pycnodysostosis and improved linear growth after growth hormone treatment

A T Soliman  1 , A Rajab, I AlSalmi, A Darwish, M Asfour
Affiliations

Defective growth hormone secretion in children with pycnodysostosis and improved linear growth after growth hormone treatment

A T Soliman et al. Arch Dis Child. 1996 Sep.

Abstract

Short stature is a characteristic feature of pycnodysostosis. We report defective growth hormone secretion in response to provocation and low insulin-like growth factor-I (IGF-I) concentration in five out of six patients with pycnodysostosis. Physiological replacement with growth hormone increased IGF-I concentration and improved linear growth in these children.

PubMed Disclaimer

References

    1. J Pediatr. 1966 Jul;69(1):131-3 - PubMed
    1. Am J Dis Child. 1968 Jul;116(1):70-7 - PubMed
    1. Acta Paediatr Scand. 1974 May;63(3):437-42 - PubMed
    1. JAMA. 1965 Mar 1;191:715-7 - PubMed
    1. J Radiol. 1984 Oct;65(10):689-95 - PubMed

Substances