Case Reports
Proximal cutaneous necrosis in association with chronic renal failure
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Case Reports
Proximal cutaneous necrosis in association with chronic renal failure
Br J Dermatol.
1996 Nov.
Abstract
We report two patients with renal failure who developed painful symmetrical ulceration over the proximal thighs and abdominal wall. Histological examination of the ulcerated areas revealed intravascular calcification. This phenomenon has been termed calciphylaxis and is a rare complication of renal failure. The pathogenesis is poorly understood. However, abnormalities of calcium/phosphate metabolism and of coagulation are important.
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