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Review
. 1996 Dec;8(6):394-7.

Folic acid to prevent neural tube defects: scientific advances and public health issues

J L Mills  1 , M R Conley
Affiliations
  • PMID: 8979009
Review

Folic acid to prevent neural tube defects: scientific advances and public health issues

J L Mills et al. Curr Opin Obstet Gynecol. 1996 Dec.

Abstract

Folic acid prevents some neural tube defects by correcting abnormal homocysteine metabolism. A defective gene coding for a homocysteine-related enzyme has been shown in people with neural tube defects. An extensive educational campaign will be required to alert women to the need to take 0.4 mg/day of folic acid during their childbearing years.

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