Exophilin A, a new antibiotic from a marine microorganism Exophiala pisciphila
- PMID: 8982339
- DOI: 10.7164/antibiotics.49.1105
Exophilin A, a new antibiotic from a marine microorganism Exophiala pisciphila
Abstract
Exophilin A, a new antibacterial compound, was discovered in the culture of the marine microorganism Exophiala pisciphila NI10102, which was isolated from a marine sponge Mycale adhaerens. The absolute chemical structure of exophilin A was elucidated as a trimer of (3R,5R)-3,5-dihydroxydecanoic acid by spectroscopic methods and analyses of a degradative product. Exophilin A showed antimicrobial activity against Gram-positive bacteria.
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