[Antimutagenic activity of tryptophan]
- PMID: 898275
[Antimutagenic activity of tryptophan]
Abstract
Antimutagenic activity of tryptophan in concentrations of 2-10(-3), 1-10(-2), and 5-10(-2) M was found in Allium cepa L. seedlings. These concentrations of tryptophan inhibit cell mitotic activity. By decreasing the frequency of spontaneous mutations and suppressing the mitotic activity of cells, tryptophan affects various functions of cells. The spectrum of chromosome mutations in tryptophan-treated seedlings does not differ from that observed under natural conditions.
Similar articles
-
[A cytogenetic analysis of the antimutagenic action of alpha-tocopherol on spontaneous and radiation-induced chromosomal mutations].Genetika. 1975;10(7):12-17. Genetika. 1975. PMID: 1225737 Russian.
-
Effects of the fungicide tridemorph on mitosis in Allium cepa.Cytobios. 1982;34(135-36):181-90. Cytobios. 1982. PMID: 7172757
-
Genotoxicity of five food preservatives tested on root tips of Allium cepa L.Mutat Res. 2007 Jan 10;626(1-2):4-14. doi: 10.1016/j.mrgentox.2006.07.006. Epub 2006 Sep 26. Mutat Res. 2007. PMID: 17005441
-
[Study of the inhibition of mitotic activity in the rat liver].Tsitol Genet. 1975 Jul-Aug;9(4):303-6. Tsitol Genet. 1975. PMID: 1209738 Russian.
-
[Studies on chemical constituents of the seeds of Allium cepa].Zhong Yao Cai. 2008 Feb;31(2):222-3. Zhong Yao Cai. 2008. PMID: 18619265 Chinese.