[Perforated synapses of the neocortex and their role in the reorganization of the interneuronal relations in the postischemic period (a morphometric study)]

Abstract

The influence of sudden systemic hemostasis on the change dynamics of numerical density of perforated (PS) and non-perforated (NS) interneuronal synaptic contacts in cerebral sensomotor cortex layer 1 were studied in albino rats during 30 postischemic days using electron microscopy and morphometric methods of examining the material treated with osmium and contrasted with phosphotungstic acid. Regularities of junction and disjunction mechanisms realization in arising PS from NS in diverse postischemic terms were demonstrated. A significant role of PS appearance in reorganization of neocortical neuronal interrelations is shown.