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Review
. 1996:104 Suppl 3:17-20.
doi: 10.1055/s-0029-1211673.

The non-obese diabetic (NOD) mouse: an animal model for autoimmune thyroiditis

M C Many  1 , S Maniratunga, J F Denef
Affiliations
Review

The non-obese diabetic (NOD) mouse: an animal model for autoimmune thyroiditis

M C Many et al. Exp Clin Endocrinol Diabetes. 1996.

Abstract

The NOD mouse, an ideal model for insulin-dependent diabetes mellitus, is also useful to study the pathogenesis of autoimmune thyroiditis. Spontaneous thyroiditis greatly varies in frequency among NOD colonies, but Hashimoto-like thyroiditis can be induced in two experimental models: goiter involution after iodide administration and immunization by TSH receptor, described hereunder.

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