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Review
. 1996 May;17(5):209-12.
doi: 10.1016/0167-5699(96)30013-3.

Integrins as promiscuous signal transduction devices

H R Petty  1 , R F Todd 3rd
Affiliations
Review

Integrins as promiscuous signal transduction devices

H R Petty et al. Immunol Today. 1996 May.

Abstract

Recent studies suggest physical and functional interactions of glycosylphosphatidylinositol (GPI)-linked proteins (CD14, CD16b and CD87) with leukocyte beta 2 integrins. As discussed in this article, it now appears that beta 2 integrins relay proinflammatory information from GPI-anchored membrane receptors to the cytoplasm via exodomain interactions.

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