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Review
. 1996;25(7):710-5.

[Uterine leiomyosarcomas: a surprising pathology. Review of the literature. Six case reports]

[Article in French]
M Durand-Réville  1 , P Dufour, D Vinatier, E Martin de Lassalle, J P Lucot, J C Monnier, M Lecomte-Houcke, F Puech
Affiliations
  • PMID: 8991905
Review

[Uterine leiomyosarcomas: a surprising pathology. Review of the literature. Six case reports]

[Article in French]
M Durand-Réville et al. J Gynecol Obstet Biol Reprod (Paris). 1996.

Abstract

Objective: The aim of this study was to determine the clinical features and laboratory tests which define a population with a high risk of leiomyosarcoma.

Method: A retrospective analysis of 660 hysterectomies performed between 1989 and 1994 was conducted. There were 414 cases of leiomyoma and 6 leiomyosarcomas (1.4%).

Results: The indication for hysterectomy was complication of fibromyomatous uterus in all cases. Diagnosis of leiomyosarcoma was never suspected before surgery and the pathology examination. Complimentary radiotherapy was given in 2 patients among the 6 with leiomyosarcoma. Mean survival was 35 months. There were no cases of recurrence or metastasis. None of the laboratory tests performed provided clues to diagnosis.

Conclusion: Physicians should be aware of possible misdiagnosis of a leiomyosarcoma when proposing medical treatment of uterine fibroma.

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