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Meta-Analysis
. 1996;193(4):300-3.
doi: 10.1159/000246274.

Psoriasis of the nails associated with disability in a large number of patients: results of a recent interview with 1,728 patients

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Meta-Analysis

Psoriasis of the nails associated with disability in a large number of patients: results of a recent interview with 1,728 patients

E M de Jong et al. Dermatology. 1996.

Abstract

Background and objective: Occurrence rates of clinical features of nail psoriasis vary considerably in the literature. Little information is available on subjective complaints of patients affected by psoriasis of the nails.

Method: Interviews with 1,728 psoriatic patients concerning their nail changes and complaints are reviewed.

Results: The results indicate that pitting and deformation are the most common clinical aberrations in psoriatic nails, with a positive association between the duration of skin lesions and nail psoriasis. No relation was found between age and nail psoriasis in this group. Remarkably, 51.8% of patients suffered from pain-caused by the nail changes, and a large group of patients was restricted in their daily activities, housekeeping and/or profession (58.9, 56.1, 47.9%). Treatment was disappointing: only 19.3% showed marked improvement during treatment.

Conclusion: This indicates that psoriasis of the nails is a more important individual and social-economic problem than previously assumed and that development of new treatments is needed.

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