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Review
. 1996 Dec 1;6(12):1573-6.
doi: 10.1016/s0960-9822(02)70775-6.

Molecular chaperones: clasping the prize

M J Gething  1
Affiliations
Free article
Review

Molecular chaperones: clasping the prize

M J Gething. Curr Biol. .
Free article

Abstract

The three-dimensional structure of the substrate-binding domain of DnaK, a bacterial Hsp70, shows how such molecular chaperones can be so promiscuous in recognizing different proteins, yet so accurate in discriminating between unfolded and folded forms of their polypeptide substrates.

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