Review
doi: 10.1016/s0959-437x(96)80023-2.
Genome research and evolution in trypanosomes
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- PMID: 8994839
- DOI: 10.1016/s0959-437x(96)80023-2
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Review
Genome research and evolution in trypanosomes
Curr Opin Genet Dev.
1996 Dec.
Abstract
Trypanosoma brucei and Trypanosoma cruzi cause different human diseases. As strategies for immune evasion, T. brucei undergone antigenic variation whereas T. cruzi becomes an intracellular organism. This fundamental difference is reflected by major differences in their genome organizations. Recent comparisons of their gene sequences indicate that these two trypanosome species are highly divergent evolutionarily.
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