[Reactions of neurons and neuroglia of the cerebral cortex at different times during a post-hypoxic state]

Abstract

By means of optical and electron microscopy the authors studied some morphological symptoms of the glial reaction to hypoxia in different periods of a posthypoxic states. The obtained data were compared with neuron changes in compensatory-adaptative, reparative and pathological states developing during the same period. A study of the changes in the satellite glia was performed with a calculation of the number of nuclei and a subsequent statistical analysis of these data. The achieved data indicate that there is an increase of the amount of satellites around the neuron when the morphological signs of reparation are most expressed as well as changes of the ultrastructure in the satellites. Such facts may speak of an active involvement of the neurons in reparation. The achieved data are discussed in the aspect of their connection with astrocyte glia and oxidative metabolism.