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. 1996;75(1):7-9.
doi: 10.1159/000134445.

Mapping of the genetically independent chicken major histocompatibility complexes B@ and RFP-Y@ to the same microchromosome by two-color fluorescent in situ hybridization

V Fillon  1 , R Zoorob, M Yerle, C Auffray, A Vignal
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Mapping of the genetically independent chicken major histocompatibility complexes B@ and RFP-Y@ to the same microchromosome by two-color fluorescent in situ hybridization

V Fillon et al. Cytogenet Cell Genet. 1996.

Abstract

The chicken MHC is organized in two genetically independent gene complexes B@ and RFP-Y@. Previous studies have shown the localization of the B@ complex on a small microchromosome. By using two-color fluorescent in situ hybridization, we demonstrate the localization of the RFP-Y@ complex to the same chromosome. A recombination hot spot between the two loci might account for their independent segregation.

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