doi: 10.1159/000144885.
Effects of mitomycin C in postnatal tooth development in mice with special reference to neural crest cells
- PMID: 899679
- DOI: 10.1159/000144885
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Effects of mitomycin C in postnatal tooth development in mice with special reference to neural crest cells
Acta Anat (Basel).
1978.
Abstract
Neural crest cells in the pre- and postnatal development of mice showed a specific sensitivity to mitomycin C. In mice injected with mitomycin C 24-48 h after birth and surviving up to the 9th day, a free or attached denticle in the pulp and a fibroma or excessive cell proliferation in the dental follicle or the periodontal ligament were seen; further, a dentinoma developed.
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