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. 1979 Aug 15;35(8):1110-2.
doi: 10.1007/BF01949973.

An alkaline protease in the delayed hypersensitivity skin lesions in the guinea-pigs

An alkaline protease in the delayed hypersensitivity skin lesions in the guinea-pigs

T Kambara et al. Experientia. .

Abstract

An alkaline hemoglobinolytic protease was extracted from the delayed hypersensitivity skin lesions induced by bovine gamma-globulin as an antigen in the guinea-pig. The enzyme was heat-labile and inhibited by thiol-blocking reagents. The mol.wt. was more than 100,000 and optimal pH around 9.

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