Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 May;18(3):293-304.
doi: 10.1177/028418517701800304.

Intravenous bolus of 125I labeled meglumine diatrizoate. Early extravascular distribution

P B Dean, M Kormano

Intravenous bolus of 125I labeled meglumine diatrizoate. Early extravascular distribution

P B Dean et al. Acta Radiol Diagn (Stockh). 1977 May.

Abstract

A mixture of 125I labeled meglumine diatrizoate and 131I labeled human serum albumin was injected into the femoral vein of 26 anesthetized male rats. Measurements of the activities in cardiac blood and in different tissues of the lower extremity and in the testis were performed at time intervals ranging from 5 s to 5 min after injection. The determination of tissue uptake and distribution volumes of diatrizoate showed widely differing accumulation of contrast medium. Over 50 per cent of the intravenous bolus of diatrizoate was extravascular at 40 s.

PubMed Disclaimer

MeSH terms